Trial of Pentamidine Isothionate in Kala-Azar Cases in the Patna Medical College Hospital (Preliminary Report)

Treatment of Kala-Azar with Pentamidine Isothionate. A Study of 55 Cases

Impact of amphotericin-B in the treatment of kala-azar on the incidence of PKDL in Bihar, India.

BACKGROUND & OBJECTIVE Of the two reservoirs of infection of kala-azar i.e., patients of kala-azar and post kala-azar dermal leishmaniasis (PKDL), PKDL provides easy access for the sandfly to pick up the parasites. In the last epidemic of 1977 in India, the importance of PKDL as a potential cause of increase in number of kala-azar cases was ignored. During recent years, we found an increase in ...

The Treatment of Kala-Azar with Sodium Antimony-V-Gluconate: Preliminary Observations *The work reported in this paper was undertaken under the Endowment Fund of the Calcutta School of Tropical Medicine, aided by a grant from the Indian Research Fund Association.

A pentavalent antimony compound (Sdt. 561, solustibosan, antimony-v-hexonate, containing 20 mg. of antimony per c.cm. of solution) , that made a stable solution and could be given intramuscularly, was first introduced b) Prof. H. Schmidt, the pioneer worker on pent*1' valent antimony compounds. Kikuth and Schmidt (1938) found that this compound possessed a marked curative action in the le*,' ma...

Hydroxy Stilbamidine in the Treatment of Kala-Azar

hvdroxy stilbenc di-isothionate, is one of the aromatic diamidine compounds synthesized by Dr. A. J. Ewins, f.b.s. During the last four months, I have treated six cases of kala-azar with this drug at the School of Tropical Medicine. Calcutta. All the patients were admitted into the hospital of the School and the diagnosis was confirmed by finding the parasite, in spleen, sternum or tibia punctu...

Kala-Azar: Diagnosis and Treatment

their spleens by " spleen puncture." Certainly, most of the patients whom we see are sent to us . from the Medical College Hospital Out-patient Dispensary and by local practitioners because they have symptoms which suggest kala-azar. On the other hand, of the patients who are eventually diagnosed kala-azar in the Medical College Hospital, more than half have been admitted not as kala-azar patie...